Synthesis and characterization and biological evaluation of bivalent metal complexes with (E)-4-bromo-N'-(4-chlorobenzylidene) benzohydrazide ligand

Khalid Tuama  Abdullah; Alaa Mohammed  Etheb; Wedad Hameed  Majeed; Ahmed S.M.  Al-Janabi; Nasry Jassim  Hussien

doi:10.55214/25768484.v9i4.6551

Authors

Khalid Tuama Abdullah Department of Chemistry, College of Education for Pure Science, University of Diyala, Diyala, Iraq.
Alaa Mohammed Etheb Department of Biology, College of Science, University of Baghdad, Iraq.
Wedad Hameed Majeed Minstry of Education/ First Karkh Education Directorate, Iraq.
Ahmed S.M. Al-Janabi Department of Chemistry, College of Science, Tikrit University, Tikrit, Iraq.
Nasry Jassim Hussien Department of Chemistry, College of Education for Pure Science, University of Diyala, Iraq.

New (E)-4-bromo-N'-(4-chlorobenzylidene)benzohydrazide (BrphOH) complexes of some bivalent metal ion complexes were synthesized and analyzed through microelemental investigation, infrared spectroscopy, conductivity measurements, and 1H NMR spectroscopy. The BrphOH was bonded with the M(II) as a chelating ligand through the oxygen atom of the carbonyl group and the nitrogen atom of the azomethine group to afford octahedral complexes of the formula [MCl2(BrphOH)(H2O)2] {MII = Co (1), Ni (2), and Cu (3)}, or as a square planar complex of the type [PdCl2(BrphOH)](4), or as tetrahedral complexes of the formula [MCl2(BrphOH)] (MII = Zn (5), Cd (6), and Hg (7)). The prepared complexes were screened against Chlamydia trachomatis, Bacillus subtilis, Nosocomiicoccus ampullae, and Escherichia coli. The Palladium (II) and Nickel (II) complexes presented more advanced microbial action than the other compounds.

Section

How to Cite

Abdullah, K. T. ., Etheb, A. M. ., Majeed, W. H. ., Al-Janabi, A. S. ., & Hussien, N. J. . (2025). Synthesis and characterization and biological evaluation of bivalent metal complexes with (E)-4-bromo-N’-(4-chlorobenzylidene) benzohydrazide ligand. Edelweiss Applied Science and Technology, 9(4), 2363–2373. https://doi.org/10.55214/25768484.v9i4.6551