This paper discusses the lasting impact of research on indigenous entrepreneurship development in Nigeria, Africa. Through primary data and content analysis, it examines the contributions of prominent scholars to the infinite nature of research. It looks at mentorship in the field of entrepreneurship in connection with the ancient guild system and indigenous Igbo business mentorship. It contrasts the nature and stages of the ancient guild system with Igbo indigenous business mentorship and highlights the benefits of knowledge-sharing and collaboration. Also, the paper showcases the importance of African culture in indigenous Igbo business mentorship and its ability to shape human understanding in human capital development and entrepreneurship. Lastly, it discusses the cultural relevance of the transition of the guild system to indigenous Igbo business mentorship and hereby challenges the prevailing Western narratives concerning the value of African cultural practices, long misunderstood or condemned, and their potential to enrich entrepreneurship and national development.